A lower abundance of Roseburia has been observed in patients suffering from inflammatory bowel disease. It has also been suggested that a decrease in one particular species, Roseburia hominis, may be associated with ulcerative colitis and irritable bowel syndrome. On the other hand, elevated levels of Roseburia may be associated with weight loss and reduced glucose intolerance.

Roseburia (pronounced “rose-BERRY-ah”) is a genus, or group, of five species of bacteria named in the 1980s after American microbiologist Theodor Rosebury. Bacteria in this genus are notable for breaking down sugar, and producing a short-chain fatty acid called butyrate which is important as a food for the cells lining the colon.


1. Stanton, T. B., & Savage, A. N. D. D. C. (1983). Roseburia cecicola gen. nov., sp. nov., a Motile, Obligately Anaerobic Bacterium from a Mouse Cecum. International Journal of Systematic Bacteriology, 33(3), 618–627. 

2. Aminov, R. I., Walker, A. W., Duncan, S. H., Harmsen, H. J. M., Welling, G. W., & Flint, H. J. (2006). Molecular Diversity, Cultivation , and Improved Detection by Fluorescent In Situ Hybridization of a Dominant Group of Human Gut Bacteria Related to Roseburia spp . or Eubacterium rectale. Applied and Enviromental Microbiology, 72(9), 6371–6376.  

3. Duncan, S. H., Hold, G. L., Barcenilla, A., Stewart, C. S., & Flint, H. J. (2002). Roseburia intestinalis sp. nov., a novel saccharolytic , butyrate-producing bacterium from human faeces. International Journal of Systematic and Evolutionary Microbiology, 52, 1615–1620. 

4. Duncan, S. H., Aminov, R. I., Scott, K. P., Louis, P., Stanton, T. B., & Flint, H. J. (2006). Proposal of Roseburia faecis sp. nov., Roseburia hominis sp . nov . and Roseburia inulinivorans sp. nov., based on isolates from human faeces. International Journal of Systematic and Evolutionary Microbiology, 56, 2437–2441.  

5. Machiels, K., Joossens, M., Sabino, J., Preter, D., Arijs, I., Eeckhaut, V., Ballet, V., Claes, K., Van Immerseel, F., Verbeke, K., Ferrante, M., Verhaegen, J., Rutgeerts, P., Vermeire, S. (2014). A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis. Gut, 63 (8), 1275–1283. 

6. Tilg, H., & Danese, S. (2014). Roseburia hominis: a novel guilty player in ulcerative colitis pathogenesis? Gut, 63(8), 1204–1205.  

7. Morgan, X. C., Tickle, T. L., Sokol, H., Gevers, D., Devaney, K. L., Ward, D. V, Huttenhower, C. (2012). Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment. Genome Biology, 13(9), R79. 

8. Chassard, C., Dapoigny, M., Scott, K. P., Crouzet, L., Del’homme, C., Marquet, P., Bernalier-Donadille, A. (2012). Functional dysbiosis within the gut microbiota of patients with constipated-irritable bowel syndrome. Alimentary Pharmacology and Therapeutics, 35, 828–838 

9. Larsen, N., Vogensen, F. K., van den Berg, F. W. J., Nielsen, D. S., Andreasen, A. S., Pedersen, B. K., Jakobsen, M. (2010). Gut Microbiota in Human Adults with Type 2 Diabetes Differs from Non-Diabetic Adults. PLoS ONE, 5(2), e9085.


Welcome to uBiome!

We are the world’s first effort to map the human microbiome with citizen science. Our sequencing service provides information and tools for you to explore the populations of bacteria that live on and inside your body.

What We Do

Based on research from the NIH Human Microbiome Project, we've perfected the technology to perform large-scale microbiome studies. The knowledge we'll gain may (one day) empower people to live healthier and accelerate our understanding of the world around us. For the individual, we leverage this technology to help you better understand your own microbiome. Here's what you can learn:



An estimated 500 - 1,000 species of bacteria live in the human gut. Get the breakdown of what yours are down to the genus level.



How well does your gut metabolize caffeine? How about carbohydrates? Our NEW functionality tab lets you compare 109 different functions of your gut, and how they stack up against others.



If you’re thinking of trying something new – a new diet, probiotics, or anything else – get a “before” picture of your microbiome to compare with your “after”, and see what has changed.



Find out how you're different. Is your microbiome more like a vegan's or a heavy drinker's? Are your bacteria more or less diverse than other people of your gender? See how you measure up.



We give you the data, what will you do with it? Team up with uBiome to research the microbiome, and discover something new.



Every day, we are learning more about the human microbiome, and we hope to have many discoveries to share as we go. It’s a vast new frontier of scientific research. Thank you for being part of it with us!

What Happens Next

Kit Sample

After ordering, we will send your kit straight to you! Collect your samples with a quick swab of the site (or sites), and mail it back to us in the provided prepaid envelope.

Your samples will travel to our office in San Francisco, where theyíll be run through our state-of-the-art DNA sequencing lab. Expect to get your results back 4-6 weeks after we receive your sample.


You will then receive access to a personal dashboard (app.ubiome.com) which breaks down the types and functions of bacteria found in your sample.

Here is where you can see your diversity score as well as learn, explore, and compare everything related to your bacteria.